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ANZSCTS ASM 2024
ANZSCTS ASM 2024

Early and Long-term Outcomes of Isolated Tricuspid Valve Surgery: a 23-year Analysis of the ANZSCTS Database

Research Paper

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Institution: Department of Cardiothoracic Surgery, Gold Coast University Hospital - Queensland, Australia

Purpose: There is growing recognition that significant tricuspid valve (TV) dysfunction is both common and independently associated with increased mortality, even in the absence of left heart disease. Yet, isolated TV surgery remains infrequently performed owing to significant patient comorbidities and perceived poor surgical outcomes. We evaluated the early and long-term outcomes of isolated TV surgery using the ANZSCTS Database. Methods: All consecutive adult patients who underwent TV surgery between 2001-2023 were identified from the ANZSCTS Database (N=7068). Patients who underwent concomitant surgery (N=5562), isolated TV surgery for active infective endocarditis (N=234) or redo isolated TV surgery (N=74) were excluded. Results: A total of 1198 patients (16.9%) underwent isolated TV surgery during the study period. Mean age was 61±16 years and 52% were female. TV repair was performed in 61.5% (737/1198) patients, while 38.5% (461/1198) patients underwent TV replacement. Surrogates for late referral were frequent: 43.4% (520/1198) had NYHA III-IV symptoms, 24.1% (289/1198) were admitted with congestive heart failure, 16.5% (198/1198) had non-elective surgery status and 14.2% (171/1198) had LVEF<45%. Early in-hospital mortality was 4.1% (49/1198). Major post-operative complications included: new dialysis 2.7% (32/1198), permanent stroke 1.4% (17/1198) and permanent pacemaker 7.9% (95/1198). Kaplan-Meier survival at 90 days and at 1, 5, 10 and 15 years after isolated TV surgery was 92±1%, 89±1%, 75±2%, 59±3% and 47±6%, respectively. Long-term survival for isolated TV repair versus replacement was similar, log-rank p=0.20. Conclusion: Isolated TV surgery remains uncommonly performed and surrogates for late surgical referral were frequently observed. Despite this, rates of early mortality (4.1%) and perioperative major morbidity are lower than traditionally reported. These outcomes may serve as a basis to advocate for earlier TV surgery and may also be a benchmark for evaluating catheter-based TV interventions.

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Dr Michael Z.L. Zhu - , Dr Andrie Stroebel - , Dr Cheng He - , Dr Matthew S. Yong -